Details

Project TitleToll-like receptor-based biosensors
Track CodeUMMS09-59
Websitehttps://patents.google.com/patent/US9409968B2/en
Short Description

This invention discloses methods and compositions to detect Toll-like receptor (TLR) binding to ligands and evaluate compound for screening. Using different biosensor complexes, this technology enable

Abstract

This invention discloses methods and compositions to detect Toll-like receptor (TLR) binding to ligands and evaluate compound for screening. Using different biosensor complexes, this technology enables the diagnosis of gram positive or negative infections in a human subject. Each platform utilizes a TLR conjugated to a biosensor that detects a single TLR-ligand binding domain complementary to its cognate ligand. This technology can provide a method to select appropriate treatment for a patient with inflammatory and possibly other conditions.

 
TagsImmunological Inflammation, vaccines, immunology, immunotherapy, virology
 
Posted DateJan 24, 2017 1:09 PM

Researcher

Name
Eicke Latz
Gabor Horvath

Manager

Name
Kevin Lehman

Intellectual Property

Patent Number Issue Date Type Country of Filing
None None Other Patent None